منابع مشابه
Phage Red-Mediated Adaptive Mutation
Adaptive mutation is a process by which an organism under nonlethal selective pressure produces mutations that relieve the selective pressure (see reference 5 for a review). It is illustrated particularly well by Escherichia coli strain FC40, a strain bearing an F episome carrying a lac allele with a frameshift mutation that makes it phenotypically Lac . When FC40 is plated on lactose-minimal m...
متن کاملInduction Mechanism Description of λ Phage by Hybrid Petri Net
It is well known that just after the chromosome of λ phage is injected into an E. coli cell, it may enter either lytic or lysogenic pathways depending on the environment in the E. coli cell [3]. In [2], we provided a strategy for describing gene regulatory network and succeeded in simulating a part of gene regulatory network of λ phage concerning to these pathway mechanisms by using the current...
متن کاملH-NS Mutation-Mediated CRISPR-Cas Activation Inhibits Phage Release and Toxin Production of Escherichia coli Stx2 Phage Lysogen
Shiga toxin-converting bacteriophages (Stx phages) carry the stx gene and convert nonpathogenic bacterial strains into Shiga toxin-producing bacteria. There is limited understanding of the effect that an Escherichia coli (E. coli) clustered regularly interspaced short palindromic repeats (CRISPR)-Cas adaptive immune system has on Stx phage lysogen. We investigated heat-stable nucleoid-structuri...
متن کاملPopulation Dynamics of Phage and Bacteria in Spatially Structured Habitats Using Phage λ and Escherichia coli.
UNLABELLED Bacteria living in physically structured habitats are exposed heterogeneously to both resources and different types of phages. While there have been numerous experimental approaches to examine spatially distributed bacteria exposed to phages, there is little theory to guide the design of these experiments, interpret their results, or expand the inferences drawn to a broader ecologica...
متن کاملRecombinant λ-phage nanobioparticles for tumor therapy in mice models
Lambda phages have considerable potential as gene delivery vehicles due to their genetic tractability, low cost, safety and physical characteristics in comparison to other nanocarriers and gene porters. Little is known concerning lambda phage-mediated gene transfer and expression in mammalian hosts. We therefore performed experiments to evaluate lambda-ZAP bacteriophage-mediated gene transfer a...
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 2002
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.184.13.3753-3755.2002